Eugenia Leis studied stage and costume design at the Mozarteum in Salzburg. Since then, she has worked as a costume assistant at the Bonn Theatre, the Vereinigte Städtische Bühnen Krefeld, Mönchengladbach, the Prinzregententheater in Munich, the University of Haifa in Haifa, Israel, and at the Nibelungen Festival in Worms. Leis was also responsible for the set design of numerous theatre and film projects. At the Staatstheater Mainz, she created the costume design for »Orestes« under Niklaus Helbling's direction and the stage and costume design for »Die Unverheiratete« under the direction of Jana Vetten.
In the opening play of the 40th Heidelberg Stückemarkt, »Pirsch« by Ivana Sokola, directed by Jana Vetten, Eugenia Leis was responsible for the set design and costumes. In 2024, she designes the costumes for Nora« in the Marguerre-Saal, also directed by Jana Vetten.